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 Post subject: Re: Upset Stomach with Malarone
Unread postPosted: Tue Sep 20, 2011 6:16 pm 
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Location: Red sand, why do I keep thinking of red sand?
I used Doxy, and on two occasions left my breakfast (just coffee, can't eat anything early) at the roadside.
Otherwise no problem, aside from the fact that you get sunburned quicker, so take precautions for that.

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 Post subject: Re: Epilepsy and anti-malaria medication
Unread postPosted: Tue Sep 20, 2011 6:21 pm 
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Epilepsy, epileptic medication, and antimalarial medications are different for each case, and therefore each patient should be assessed separately. There are epileptic medications that are dependent on therapeutic blood levels in order to be effective (and often, if the levels move outside these boundaries, the patient fits), and one then has to be particularly careful with the type of antimalarial used, and indeed if antimalarials should be used at all. Then there are a specific set of trigger factors peculiar to each person that need to be taken into account. Some people are fine on certain antimalarials, some are not. Hence you will notice that I do not blanket-recommend on a public site like this. Some people have sent me pm's and, where appropriate, I have given my personal advice, based in knowledge and experience. However, always consult a knowledgeable health-professional who knows how to assess epilepsy (or any disease, really) in relation to malaria risk and antimalarials.

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 Post subject: Re: Epilepsy and anti-malaria medication
Unread postPosted: Tue Sep 20, 2011 6:23 pm 
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Thanks for the update Chillx and glad that you all had a wonderful trip. :thumbs_up: :thumbs_up:

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 Post subject: Re: Malaria
Unread postPosted: Tue Sep 20, 2011 6:24 pm 
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Thanks for the info onewithnature!


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 Post subject: Re: Malaria
Unread postPosted: Tue Sep 20, 2011 6:25 pm 
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You're welcome, CarlaLo. Hope it assists your decision-making. :thumbs_up:

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 Post subject: Re: Malaria
Unread postPosted: Tue Sep 20, 2011 6:27 pm 
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FRUITBAT wrote:
Hi OWN, please can you give me some advice with regards to my recent query :
Thanks very much

Quote:
Hello forumites, my adult son is epileptic and we plan to take him to Kruger next February, however, I've always read that people taking anti-convulsants can't take anti-malaria meds. Obviously the risk of contracting malaria in the summer is much higher so am therefore worried. Would be interested to hear from any other forumites who have this same condition and what they do in this case.




Epilepsy, epileptic medication, and antimalarial medications are different for each case, and therefore each patient should be assessed separately. There are epileptic medications that are dependent on therapeutic blood levels in order to be effective (and often, if the levels move outside these boundaries, the patient fits), and one then has to be particularly careful with the type of antimalarial used, and indeed if antimalarials should be used at all. Then there are a specific set of trigger factors peculiar to each person that need to be taken into account. Some people are fine on certain antimalarials, some are not. Hence you will notice that I do not blanket-recommend on a public site like this. Some people have sent me pm's and, where appropriate, I have given my personal advice, based in knowledge and experience. However, always consult a knowledgeable health-professional who knows how to assess epilepsy (or any disease, really) in relation to malaria risk and antimalarials.

With regards to Fruitbat, I have pm'ed her some suggestions, and hope it assists her to make a sound decision. :thumbs_up:

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TR: NECTAREAN NICETIES OF THE NORTH
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 Post subject: Re: Upset Stomach with Malarone
Unread postPosted: Tue Sep 20, 2011 6:45 pm 
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I've had the same thing so I now take Doxy. Downside you have to take it for longer and have to use a sunblock as it increases sensitivity to the sun. Upside is, its much cheaper.

However I have just reread the Malarone instructions and it says not to lie down within an hour of taking it so that may be a cause of the stomach upset?

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 Post subject: Re: Upset Stomach with Malarone
Unread postPosted: Tue Sep 20, 2011 7:16 pm 
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Reads very awful this thread!!

Does to me cause,- " protection",
seems a killer itself!!!

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 Post subject: Re: Upset Stomach with Malarone
Unread postPosted: Tue Sep 20, 2011 7:58 pm 
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Without wishing to be too graphic my problem wasnt nausea but rather the "other end of the spectrum" which was even worse so I am afraid anti-nausea tablets wont help. I have just been reading up on the alternatives to Malarone and it still seems to be the best of a bad bunch which isnt great news. The alternative is going without and using buckets of mosquito repellant and long sleeves and pants which is probably not the best idea but sounds way more attractive than spending 10 days doubled over....

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 Post subject: Re: Epilepsy and anti-malaria medication
Unread postPosted: Tue Sep 20, 2011 9:16 pm 
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There is a "natural" antimalaria product on the market too. artimisia ( not sure about spelling). manufactured by Nordmans. I prefer to use this when going to a malaria area, not a big fan of Doxy.

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 Post subject: Re: Upset Stomach with Malarone
Unread postPosted: Tue Sep 20, 2011 10:42 pm 
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Like you I took many years Malarone... and last time (2009) I was so sick I stop the medication :shock:
This year (2011) I asked for something else... they (University Policlinic of Lausanne) give me SUPRACYCLINE tabs (Doxycycline) and give me something "Motilium" against upset.
But, there is a but, SUPRACYCLINE is a little bit new and maybe could do some skin problems with the sun... for me all was ok during more than 2 months and without need of Motilium :D

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 Post subject: Re: Epilepsy and anti-malaria medication
Unread postPosted: Wed Sep 21, 2011 8:59 am 
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WFG, I would be very interested to know if the product you're using for malaria prophylaxis contains ONLY the drug artemisinin, and what dosage and dosage interval (how many times a day) you are using?

The reason I ask is because, although artemisinin, and its derivatives, such as artemeter, are highly effective against malaria, the WHO (World Health Organisation) is very concerned that use of the drug on it own - and not in combination with another antimalarial - is likely to cause a disaster situation where resistance to artemisinin builds up (for example, in Cambodia).

The main reason that the WHO is so concerned is because artemesinin has proven to be a highly effective TREATMENT for patients infected with uncomplicated plasmodium falciparum (the type that is prevalent in most of Africa, and generally the severest type of malaria infection). It is, i suppose you could say, a wonder drug at the moment because it seems to be giving the best results for such treatments.

Coartem is available in South Africa and many other countries world-wide, and consists of the combinaton of artemether and lumefantrine. In treatment of uncomplicated falciparum malaria, the artemeter initially eliminates a large amount of the parasite, but then lumefantrine is needed to eliminate the rest of the parasite. Artemeter on its own does not eliminate all of the parasite, and resistance of the parasite to the drug then increases rapidly.

In addition, artemisinin has a very short half-life in the body - which essentially means the amount of time the drug remains in the body in an active state before being eliminated to half its original level. This means that, for artemisinin to be effective for antimalarial prevention, it would have to be taken multiple times a day!

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 Post subject: Re: Epilepsy and anti-malaria medication
Unread postPosted: Wed Sep 21, 2011 10:00 am 
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PM'ed OWN with the website's details.

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 Post subject: Re: Upset Stomach with Malarone
Unread postPosted: Wed Sep 21, 2011 10:31 am 
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My 12 year old son and I always take Mefliam and have never experienced any bad reactions. Everyone I have spoken to says it is the one with the least side effects.

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 Post subject: Re: Upset Stomach with Malarone
Unread postPosted: Wed Sep 21, 2011 12:20 pm 
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I agree with Flutterby; mefloquine (brand names Larium or Mefliam) is excellent. I haven't experienced any side-effects from it in all the years that I've taken it. And one only takes it once a week, not everyday like some of the other malaria prophylaxis.


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